Percutaneous vertebroplasty for osteoporotic compression fracture: Multivariate study of predictors of new vertebral body fracture
Percutaneous vertebroplasty for osteoporotic compression fracture: Multivariate study of predictors of new vertebral body fracture
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DOI：
10.1007/s00270-005-0138-5
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发表时间：
2006-08-01
影响因子：
2.9
通讯作者：
Sawada, Satoshi
中科院分区：
文献类型：
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作者：
Komemushi, Atsushi;Tanigawa, Noboru;Sawada, Satoshi
目的：目的探讨椎体成形术后新发压缩骨折的危险因素和相对危险度。方法：最初，我们纳入了104例骨质疏松性椎体压缩骨折患者。104例患者中，共有83例在椎体成形术后4周以上来我院进行随访检查。从这83例患者获得的数据进行Logistic回归分析，以确定复发性压缩性骨折的相对风险，使用13个不同的factors.Results：我们确定了59个新的骨折30的83例：41个新的骨折相邻的椎骨治疗椎骨;和18个新的骨折不相邻的椎骨治疗椎骨。新骨折发生在邻近治疗椎骨的椎骨中的频率显著高于不邻近治疗椎骨的椎骨。只有骨水泥漏入椎间盘是椎体成形术后新发椎体骨折的重要预测因素（比值比= 4.633）。以下协变量均与新发骨折风险增加无关：年龄、性别、骨矿物质密度、椎体成形术手术次数、每次手术治疗的椎骨数量、治疗的椎骨的累积数量、治疗的椎骨之间是否存在单个未治疗的椎骨、治疗的椎骨之间是否存在多个未治疗的椎骨、每次手术注射的骨水泥量，注入的骨水泥的累积量、骨水泥渗漏到椎骨周围的软组织中以及骨水泥渗漏到静脉中。
Purpose: To investigate the risk factors and relative risk of new compression fractures following vertebroplasty.Methods: Initially, we enrolled 104 consecutive patients with vertebral compression fractures caused by osteoporosis. A total of 83 of the 104 patients visited our hospital for follow-up examinations for more than 4 weeks after vertebroplasty. Logistic regression analysis of the data obtained from these 83 patients was used to determine relative risks of recurrent compression fractures, using 13 different factors.Results: We identified 59 new fractures in 30 of the 83 patients: 41 new fractures in vertebrae adjacent to treated vertebrae; and 18 new fractures in vertebrae not adjacent to treated vertebrae. New fractures occurred in vertebrae adjacent to treated vertebrae significantly more frequently than in vertebrae not adjacent to treated vertebrae. Only cement leakage into the disk was a significant predictor of new vertebral body fracture after vertebroplasty (odds ratio = 4.633). None of the following covariates were associated with increased risk of new fracture: age, gender, bone mineral density, the number of vertebroplasty procedures, the number of vertebrae treated per procedure, the cumulative number of vertebrae treated, the presence of a single untreated vertebra between treated vertebrae, the presence of multiple untreated vertebrae between treated vertebrae, the amount of bone cement injected per procedure, the cumulative amount of bone cement injected, cement leakage into the soft tissue around the vertebra, and cement leakage into the vein.