Electron microscopic study of bullous pemphigoid.
Electron microscopic study of bullous pemphigoid.
复制标题
大疱性类天疱疮的电子显微镜研究。
作者：
G. Schaumburg‐Lever;C. Orfanos;W. P. Lever
本文用电镜观察了大疱性类天疱疮的水疱形成。水疱的发展过程可分为三个阶段：（1）真皮和表皮有明显的水肿，真皮中有相当明显的细胞浸润。基底细胞的突起与浸润细胞接触。(2)基底层显示不连续性。嗜酸性白细胞迁移到表皮和脱髓鞘。(3)在发育完全的水疱中，通常没有基膜。我们在大疱性类天疱疮中的发现与疱疹样皮炎中的发现难以区分。
Blister formation in inflamed lesions of bullous pemphigoid were studied by electron microscopy. Three stages can be distinguished during the development of a blister: (1) There is marked edema in the dermis and epidermis and a rather pronounced cellular infiltrate in the dermis. Projections of basal cells are in contact with infiltrate cells. (2) The basal lamina shows discontinuities. Eosinophilic leukocytes migrate into the epidermis and degranulate. (3) In the fully developed blister the basal lamina is usually absent. Our findings in bullous pemphigoid are indistinguishable from those described in dermatitis herpetiformis.