Outcome of pregnancies with rapid embryonic heart rates in the early first trimester
Outcome of pregnancies with rapid embryonic heart rates in the early first trimester
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DOI：
10.2214/ajr.175.1.1750067
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发表时间：
2000-07-01
影响因子：
5
通讯作者：
Chow, JS
中科院分区：
文献类型：
--
作者：
Doubilet, PM;Benson, CB;Chow, JS
OBJECTIVE.我们进行了一项研究，以确定正常胚胎心率的上限或之前7.0周的胎龄，并评估妊娠的结果，其中早期胚胎心率是快速的。我们在1993年1月至1998年6月间进行的2817例妊娠7.0周或之前的超声检查中记录了胚胎心率。两个胎龄范围（6.3周前和6.3-7.0周）的正常心率上限计算为两个值的平均值：平均心率+ 1.96标准差和我们人群中2.5%的胚胎测量的心率。将胎心率加快组的妊娠结局与胎心率正常的对照组的妊娠结局进行比较。孕6.3周前正常心率上限为134次/分，孕6.3-7.0周为154次/分。41个胚胎早期心率较快，妊娠早期结局已知，其中37个（90.2%）在妊娠早期结局结束时存活。37个妊娠早期存活者中有33个（4个在分娩前失访）的妊娠结局可用，其中30个（90.9%）为健康新生儿。这些短期和长期结果与早期心率正常的对照组胚胎无显著差异（p > 0.20，Fisher精确检验）。快速的早期胚胎心率是在6.3周之前至少每分钟135次，或者在6.3-7.0周至少每分钟155次。胚胎早期心率较快的妊娠预后良好，正常结局的可能性很高。
OBJECTIVE. We conducted a study to determine the upper limits of normal embryonic heart rate at or before 7.0 weeks' gestational age and to assess outcome of pregnancies in which the early embryonic heart rate is rapid.SUBJECTS AND METHODS. We recorded embryonic heart rates in 2817 sonograms at or before 7.0 weeks' gestation performed between January 1993 and June 1998. The upper limit of normal heart rate in two gestational age ranges (before 6.3 weeks and 6.3-7.0 weeks) was computed as the average of two values: mean heart rate + 1.96 standard deviations and the rate above which 2.5% of embryos in our population were measured. Pregnancy outcome in cases with rapid embryonic heart rates was compared with pregnancy outcome in a control group with normal rates.RESULTS. The upper limit of normal heart rate was 134 heats per minute before 6.3 weeks' gestation and 154 bears per minute at 6.3-7.0 weeks' gestation. Forty-one embryos had rapid early heart rates and known first-trimester outcome, of which 37 (90.2%) were alive at the end of the first trimester Pregnancy outcome was available in 33 of the 37 first-trimester survivors (four were lost to follow-up before delivery), and 30 of these 33 (90.9%) were healthy neonates. These short- and long-term outcomes were not significantly different from those of the control group of embryos with normal early heart rates (p > 0.20, Fisher's exact test).CONCLUSION. A rapid early embryonic heart rate is one that is at least 135 beats per minute before 6.3 weeks or at least 155 beats per minute at 6.3-7.0 weeks. Pregnancies in which the embryo has a rapid early heart rate have a good prognosis, with a high likelihood of normal outcome.