Modifiable lifestyle factors and ovarian cancer incidence in women
Modifiable lifestyle factors and ovarian cancer incidence in women
复制标题
DOI：
10.5604/12321966.1233565
复制
发表时间：
2018-01-01
影响因子：
1.7
通讯作者：
Bojar, Iwona
中科院分区：
文献类型：
--
作者：
Plagens-Rotman, Katarzyna;Chmaj-Wierzchowska, Karolina;Bojar, Iwona
导言。正确的饮食在预防恶性肿瘤方面起着重要作用。通过对日常饮食进行一些改变，可以降低罹患这种疾病的风险。最重要的变化涉及饮食中的脂肪量、膳食纤维、食物中的抗氧化剂以及对恶性肿瘤的发展有重大影响的物质的减少。该研究的目的是分析选定的可改变的生活方式因素对卵巢癌发展的影响。材料和方法。这项研究覆盖了健康女性和被诊断为卵巢癌的女性。共有850名年龄在21-84岁之间的女性接受了研究。这项研究包括2011-2013年间前往波兰波兹南医科大学妇产科医院就诊的妇女。根据手术中获得的组织病理学检查，确诊为恶性卵巢癌的患者符合研究条件。每周食用几次水果和蔬菜的受访者与完全不吃水果和蔬菜的女性相比，优势比OR=0.29水平；95%可信区间为0.04-2.01(p=.2085)。每周多次食用100克炸薯条和薯片，卵巢癌的发病率会增加2倍。这组女性的OR值为2.06；95%可信区间为0.53-7.99(p=.2966)。应该引入富含水果和蔬菜的饮食，包括鳞茎类蔬菜和含有全谷物的谷物产品。建议取消食用受欢迎的快餐。
Introduction. A correct diet plays an important role in the prevention of malignant tumours. The risk of the disease may be reduced by introducing a number of changes to the daily diet. The most important changes concern the amount of fat in the diet, dietary fibre, antioxidants in the food and the reduction of substances having a significant impact on the development of malignant tumours.Objective. The aim of the study is to analyse the role of selected modifiable lifestyle factors affecting the development of ovarian cancer.Materials and method. The study covered healthy women and women with diagnosed ovarian cancer. A total of 850 women aged between 21-84 were studied. The study included women visiting the Gynaecology and Obstetrics Hospital of the University of Medical Sciences in Poznan, Poland, between 2011-2013. Patients recognized with malignant ovarian cancer were qualified into the study based on the histopathological examination of the material obtained during surgery.Results. Respondents who consumed fruit and vegetables several times a week have the odds ratio OR = 0.29 level; 95% CI 0.04-2.01 (p =.2085), compared to women not consuming fruit and vegetables at all. Consumption of 100 g of French fries and potato chips several times a week, results in a 2-fold increase in ovarian cancer. The OR for this group of women amounts to 2.06; 95% CI 0.53-7.99 (p=.2966).Conclusions. A diet rich in fruit and vegetables, including bulb vegetables, and grain products containing whole grains, should be introduced. It is recommended that the consumption of popular fast foods be eliminated.