Indwelling pleural catheter and successful autopleurodesis of refractory inflammatory lupus effusion
Indwelling pleural catheter and successful autopleurodesis of refractory inflammatory lupus effusion
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DOI：
10.1002/rcr2.621
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发表时间：
2020-10-01
影响因子：
0.8
通讯作者：
Ban, Andrea Yu-Lin
中科院分区：
文献类型：
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作者：
Ng, Boon Hau;Nik Abeed, Nik Nuratiqah;Ban, Andrea Yu-Lin
留置胸腔导管是治疗难治性恶性胸腔积液的有效手段。它可以通过间歇性缓解积液症状来缓解症状，并改善生活质量。其在良性胸腔积液中的应用主要来自回顾性研究、病例系列和病例报告。狼疮渗出是常见的，引起最小的症状，通常对类固醇治疗或免疫抑制剂有反应。难治性狼疮性渗出不太常见，治疗可能需要侵入性胸膜切除术。我们报告一位52岁的女性，其系统性红斑狼疮（SLE）的第一个表现是类固醇和免疫抑制剂治疗无效的胸腔积液。她成功地实现了自发性胸膜固定术，并在3个月时进行间歇性IPC引流。
Indwelling pleural catheter (IPC) is a useful tool for refractory malignant pleural effusions (MPEs). It allows palliation by intermittent symptomatic relief of the effusion and improves quality of life. Its use in benign pleural effusions comes mainly from retrospective studies, case series, and case reports. Lupus effusion is common, causes minimal symptoms, and usually responds to either steroid therapy or immunosuppressants. Refractory lupus effusion is less common and treatment may require invasive surgical pleurectomy. We describe a 52-year-old woman whose first presentation of systemic lupus erythematosus (SLE) was a pleural effusion refractory to steroids and immunosuppressants. She successfully achieved spontaneous pleurodesis with intermittent IPC drainage at three months.