Correlates of Validity of Self-Reported Methamphetamine Use among a Sample of Dependent Adults.
Correlates of Validity of Self-Reported Methamphetamine Use among a Sample of Dependent Adults.
复制标题
受抚养成年人样本中自我报告的甲基苯丙胺使用有效性的相关性。
DOI：
10.1080/10826084.2018.1432649
复制
发表时间：
2018
影响因子：
2
通讯作者：
Santos,Glenn-Milo
中科院分区：
文献类型：
--
作者：
Rowe,Christopher;Vittinghoff,Eric;Colfax,Grant;Coffin,PhillipO;Santos,Glenn-Milo
Background: Self-reported data are widely used in substance-use research, yet few studies have assessed the validity of self-reported methamphetamine use compared to biological assays.Objectives: We sought to assess the validity and correlates of validity of self-reported methamphetamine use compared to urine toxicology (UTOX).Methods: Using a sample of methamphetamine-dependent individuals enrolled in a randomized controlled pharmacotherapy trial in the United States (n= 327 visits among 90 participants), we calculated sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the kappa coefficient of self-reported methamphetamine use in the past 3 days compared to UTOX, as well as the NPV of self-reported methamphetamine use over an extended recall period of 1 month. We used multivariable logistic regression models to assess correlates of concordance between self-reported methamphetamine use and UTOX.Results: The sensitivity of self-reported methamphetamine use in the past 3 days was 86.7% (95% confidence intervals (95%CI): 81.4%–91.4%), the specificity was 85.3% (77.7–91.3), the PPV was 91.5% (86.9–94.8), and the NPV was 78.0% (69.4–86.1), compared to UTOX (kappa = 0.71). The NPV over the extended recall period was 70.6% (48.0–85.7). In multivariable analyses, validity of self-reported methamphetamine use was higher for older participants but lower during follow-up compared to baseline and when polysubstance use or depressive symptoms were reported.Conclusions/Importance: Our sample of methamphetamine-dependent adults reported recent methamphetamine use with high validity compared to UTOX. Validity increased with age but decreased when participants reported depressive symptoms or polysubstance use as well as later in the study timeline and during longer recall periods.
