RNAi and chromatin in T cell development and function.
RNAi and chromatin in T cell development and function.
复制标题
T 细胞发育和功能中的 RNAi 和染色质。
DOI：
10.1016/j.coi.2008.03.013
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发表时间：
2008
影响因子：
7
通讯作者：
Wilson,ChristopherB
中科院分区：
文献类型：
--
作者：
Merkenschlager,Matthias;Wilson,ChristopherB
Small noncoding RNAs including small interfering RNAs (siRNAs) and microRNAs (miRNAs) have emerged as important regulators of gene expression. They control transcription through changing the structure of chromatin and regulate mRNA stability and translation at the post-transcriptional level. This year has seen exciting progress in our ability to map chromatin structure and chromatin-associated factors genome-wide as well as striking examples how individual miRNAs affect the development and the function of the immune system.
