Incidence of rheumatoid arthritis in Finland during 1980-1990
Incidence of rheumatoid arthritis in Finland during 1980-1990
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DOI：
10.1136/ard.55.9.608
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发表时间：
1996-09-01
影响因子：
27.4
通讯作者：
Laakso, M
中科院分区：
文献类型：
--
作者：
KaipiainenSeppanen, O;Aho, K;Laakso, M
目的：了解风湿性关节炎在芬兰的发病率及其近期发展趋势。方法：本研究涵盖了芬兰21个中心医院区中的5个，在1980年、1985年和1990年的三年间，根据全国疾病保险计划，有权获得治疗类风湿性关节炎的特殊报销药物的受试者(人口基础约为100万成年人)。结果：1980年和1985年，符合美国风湿病协会1987年分类标准的类风湿性关节炎的年发病率为39%，占大于或等于16岁的人口的100000。类风湿因子(RF)阳性关节炎和RF阴性多发性关节炎的合并发病率为46/100000。与前几年相比，1990年RF阴性的类风湿性关节炎病例数量下降了约40%。下降趋势具有统计学意义(P=0.008)。结论--芬兰RF阴性类风湿关节炎发病率的下降可能反映了环境的变化，特别是影响RF阴性疾病风险的环境变化。
Objective-To obtain information on the incidence of rheumatoid arthritis and on its recent trends in Finland.Methods-The study covered those subjects entitled to receive specially reimbursed medication for rheumatoid arthritis under the nationwide sickness insurance scheme in five out of 21 central hospital districts in Finland (population basis about one million adults) during three years: 1980, 1985, and 1990.Results-The annual incidence of rheumatoid arthritis in 1980 and 1985, satisfying the American Rheumatism Association 1987 classification criteria, was 39/100000 of the population greater than or equal to 16 years of age. The combined incidence of rheumatoid factor (RF) positive arthritis and RF negative polyarthritis was 46/100000. A decline of approximately 40% occurred in the number of RF negative rheumatoid arthritis cases in 1990 compared with the earlier years. The declining trend was statistically significant (P = 0.008).Conclusion-The decline in incidence of RF negative rheumatoid arthritis in Finland may reflect changes in the environment specifically affecting the risk of RF negative disease.