Paralytic syndromes associated with noninflammatory cytoplasmic or nuclear neuronopathy. Acute paralytic disease in Mexican children, neuropathologically distinguishable from Landry-Guillain-Barré syndrome.
Paralytic syndromes associated with noninflammatory cytoplasmic or nuclear neuronopathy. Acute paralytic disease in Mexican children, neuropathologically distinguishable from Landry-Guillain-Barré syndrome.
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墨西哥儿童与非炎症性细胞质或核神经元病相关的麻痹综合征，在神经病理学上与兰德里-吉兰-巴利综合征有区别。
DOI：
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发表时间：
1969
期刊：
影响因子：
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通讯作者：
A. Sabin
中科院分区：
文献类型：
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作者：
M. Ramos‐Álvarez;L. Bessudo;A. Sabin
对57名患有急性下运动神经元麻痹疾病的墨西哥儿童进行的尸检研究表明，32名儿童患有脊髓灰质炎，25名儿童的中枢神经系统没有炎症变化。在后一组中，10例表现出符合Landry-Guillain-Barre综合征诊断的神经病理学变化; 8例显示大部分下运动神经元广泛的染色质溶解，被归类为“细胞质神经元病”; 7例显示嗜银，大部分下运动神经元的核变性变化，但没有染色质溶解，被归类为“核神经元病”。“在Landry-Guillain-Barre组中，70%的患者瘫痪和死亡之间的间隔时间超过一周（10至30天），75%的细胞质神经元病组为一周或更短，86%的核神经元病组为一周或更短。
Postmortem studies on 57 Mexican children with acute, lower motor neuron paralytic disease indicated that 32 had poliomyelitis and 25 had no inflammatory changes in the central nervous system. In the latter group, ten exhibited neuropathologic changes compatible with a diagnosis of Landry-Guillain-Barre syndrome; eight, showing extensive chromatolysis of the majority of lower motor neurons, were categorized as "cytoplasmic neuronopathy"; and seven, showing an argyrophil, degenerative change of the nuclei of the majority of lower motor neurons but no chromatolysis, were categorized as "nuclear neuronopathy." The interval between onset of paralysis and death was longer than one week (10 to 30 days) in 70% of the Landry-Guillain-Barre group, one week or less in 75% of the cytoplasmic neuronopathy group, and less than one week in 86% of the nuclear neuronopathy group.