NEW INSTRUMENT FOR CONTINUOUS MEASUREMENT OF TISSUE BLOOD-FLOW BY LIGHT BEATING SPECTROSCOPY

NEW INSTRUMENT FOR CONTINUOUS MEASUREMENT OF TISSUE BLOOD-FLOW BY LIGHT BEATING SPECTROSCOPY
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DOI:
10.1109/tbme.1980.326686
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发表时间:
1980-01-01
影响因子:
4.6
通讯作者:
OBERG, PA
OBERG, PA
中科院分区:
工程技术2区
文献类型:
--
作者:
NILSSON, GE;TENLAND, T;OBERG, PA

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本文报道了一种基于激光多普勒原理的局部组织血流测量仪。本文讨论了光拍频光谱学的理论背景,并描述了一种能抑制激光模干涉和宽带光束振幅噪声的探测技术。代替使用单个平方律光电探测器,引入了差分检测器技术,该差分检测器技术将共模噪声降低到可忽略的水平,而不影响血流相关信号。这种新仪器已被证明是高度稳定和灵敏的。组织血流的连续记录可以在实验室和床边进行。
A new instrument for measurement of regional tissue blood flow based on the laser Doppler principle is reported. The theoretical background of light beating spectroscopy is discussed and a detection technique which makes possible the suppression of the adverse effects of laser-mode interference and wide-band beam amplitude noise is described. Instead of using a single square-law photodetector a differential detector technique is introduced that reduces common-mode noise to a negligible level, without influencing the blood flow related signal. The new instrument has proved to be highly stable and sensitive. Continuous recordings of tissue blood flow can be performed in the laboratory as well as at the bedside.