Transport of single cells using an actin bundle–myosin bionanomotor transport system

Transport of single cells using an actin bundle–myosin bionanomotor transport system
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使用肌动蛋白束-肌球蛋白生物纳米运动运输系统运输单细胞

DOI:
10.1088/0957-4484/22/24/245101
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发表时间:
2011
期刊:
影响因子:
3.5
通讯作者:
E. Blough
E. Blough
中科院分区:
材料科学3区
文献类型:
--
作者:
H. Takatsuki;Hideyuki Tanaka;K. Rice;Madhukar B. Kolli;Siva K. Nalabotu;K. Kohama;P. Famouri;E. Blough

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研究了肌动蛋白束用于脂质体和单细胞在肌球蛋白涂层表面的传输的可能性。与用丝状肌动蛋白观察到的相比,使用肌动蛋白束的脂质体传输本质上更加线性,并且能够发生在更长的距离上。束,但不是丝状肌动蛋白,能够移动单个细胞。通过与Triton X-100孵化,实现了从捆绑包中卸货。这些数据表明,肌动蛋白捆绑可能会提高肌球蛋白马达系统应用于纳米运输的能力。
The potential of using actin bundles for the transport of liposomes and single cells across myosin-coated surfaces is investigated. Compared to that observed with filamentous actin, the liposome transport using actin bundles was more linear in nature and able to occur over longer distances. Bundles, but not filamentous actin, were capable of moving single cells. Cargo unloading from bundles was achieved by incubation with Triton X-100. These data suggest that actin bundling may improve the ability of the myosin motor system for nanotransport applications.
DOI: 10.1152/ajpcell.1992.262.3.c714
发表时间: 1992-03-01
影响因子: --
作者:
HOMSHER, E;WANG, F;SELLERS, JR
通讯作者: SELLERS, JR
DOI: 10.1073/pnas.83.17.6272
发表时间: 1986-09-01
影响因子: 11.1
作者:
KRON, SJ;SPUDICH, JA
通讯作者: SPUDICH, JA