Strategic processing and episodic memory impairment in obsessive compulsive disorder.
Strategic processing and episodic memory impairment in obsessive compulsive disorder.
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强迫症中的策略处理和情景记忆障碍。
DOI：
10.1037//0894-4105.14.1.141
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Jenike,MA
中科院分区：
文献类型：
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作者：
Savage,CR;Deckersbach,T;Wilhelm,S;Rauch,SL;Baer,L;Reid,T;Jenike,MA
有证据表明，强迫症（OCD）的非言语记忆问题是由受损的策略处理介导的。尽管许多研究发现，强迫症患者的非文字记忆是正常的，但这些研究并没有使用旨在强调组织策略的测试。本研究采用Rey-Osterrieth复杂图形测验和加州言语学习测验对33名强迫症患者和30名正常对照者的言语和非言语记忆成绩进行了研究。强迫症患者的组织策略和自由回忆的语言和非语言措施受损。多元回归模型表明，强迫症的自由回忆问题是由受损的组织策略在学习试验中使用。因此，强迫症的言语和非言语情景记忆缺陷受到策略加工受损的影响。结果是一致的神经生物学模型提出额-纹状体系统功能障碍的强迫症。
There is evidence that nonverbal memory problems in obsessive compulsive disorder (OCD) are mediated by impaired strategic processing. Although many studies have found verbal memory to be normal in OCD, these studies did not use tests designed to stress organizational strategies. This study examined verbal and nonverbal memory performance in 33 OCD patients and 30 normal control participants with the Rey–Osterrieth Complex Figure Test and the California Verbal Learning Test. OCD patients were impaired on verbal and nonverbal measures of organizational strategy and free recall. Multiple regression modeling indicated that free recall problems in OCD were mediated by impaired organizational strategies used during learning trials. Therefore, verbal and nonverbal episodic memory deficits in OCD are affected by impaired strategic processing. Results are consistent with neurobiological models proposing frontal-striatal system dysfunction in OCD.