Prevalence of premenstrual syndrome in autism: a prospective observer-rated study
Prevalence of premenstrual syndrome in autism: a prospective observer-rated study
复制标题
DOI：
10.1177/147323000803600208
复制
发表时间：
2008-03-01
影响因子：
1.6
通讯作者：
Puri, B. K.
中科院分区：
文献类型：
--
作者：
Baydi, H.;Puri, B. K.
一项系统的、前瞻性的、分级的研究旨在确定孤独症女性中黄体晚期焦虑障碍（经前综合征）的患病率。将一组患有自闭症和学习障碍的妇女（n = 26）与一组年龄、住院状态、智力、婚姻状况、产次、行为问题和种族匹配的非自闭症学习障碍妇女（n = 36）进行比较。观察者在连续三个月经周期内，每天对每个受试者的黄体晚期焦虑障碍的DSM-IV症状进行评分。以经前DSM-IV症状增加>= 30%作为满足诊断标准的证据，孤独症组黄体晚期焦虑障碍的患病率为92%，而对照组为11%。这种差异具有高度统计学意义。这项研究的主要结论是，与匹配的对照组相比，患有自闭症的女性经前综合征明显增加。
A systematic, prospective observer-rated study was carried out to determine the prevalence of late luteal phase dysphoric disorder (premenstrual syndrome) in women with autism. A group of women with autism and learning disability (n = 26) was compared with a group of women with a non-autism learning disability (n = 36) matched for age, in-patient status, intelligence, marital status, parity, behavioural problems and ethnicity. Observers rated DSM-IV symptoms of late luteal phase dysphoric disorder every day from each subject over three consecutive menstrual cycles. Using a premenstrual increase in DSM-IV symptoms of >= 30% as evidence of fulfilment of diagnostic criteria, the prevalence of late luteal phase dysphoric disorder was 92% in the autism group compared with 11% in the control group. This difference was highly statistically significant. The principal conclusion from this study is that there is a marked increase in premenstrual syndrome in women with autism compared with matched controls.