Stimulatory effect of morning bright light on reproductive hormones and ovulation: results of a controlled crossover trial.
Stimulatory effect of morning bright light on reproductive hormones and ovulation: results of a controlled crossover trial.
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DOI：
10.1371/journal.pctr.0020007
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发表时间：
2007-02-09
期刊：
影响因子：
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通讯作者：
Samoilova, Elena A
中科院分区：
文献类型：
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作者：
Danilenko, Konstantin V;Samoilova, Elena A
目的：研究表明，在月经周期异常长或冬季抑郁的女性中，光照会缩短月经周期，这表明人造光会影响生殖激素和排卵。设计：安慰剂对照，交叉，平衡order.SETTING：医疗中心和参与者的家在新西伯利亚（55度N），Russia.PARTICIPANTS：22名妇女，年龄19-37岁，基线月经周期长度28.1-37.8天，没有临床上明显的内分泌异常完成了这项研究。该研究持续了两个月经周期分开至少一个off-protocol cycle.INTERVENTIONS：在一个实验周期，明亮的光管理在家里1周，在41厘米发射白色光45分钟后不久醒来的灯箱在4,300勒克斯。在另一个实验周期中，
OBJECTIVES: Studies have shown a shortening of the menstrual cycle following light exposure in women with abnormally long menstrual cycles or with winter depression, suggesting that artificial light can influence reproductive hormones and ovulation. The study was designed to investigate this possibility.DESIGN: Placebo-controlled, crossover, counterbalanced order.SETTING: Medical centres and participants' homes in Novosibirsk (55 degrees N), Russia.PARTICIPANTS: Twenty-two women, aged 19-37 years, with baseline menstrual cycle length 28.1-37.8 d and no clinically evident endocrine abnormalities completed the study. The study lasted for two menstrual cycles separated by at least one off-protocol cycle.INTERVENTIONS: During one experimental cycle, bright light was administered at home for 1 wk with a light box emitting white light at 4,300 lux at 41 cm for 45 min shortly after awakening. During the other experimental cycle, dim light was