TandTRAQ:: an open-source tool for integrated protein identification and quantitation
TandTRAQ:: an open-source tool for integrated protein identification and quantitation
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DOI：
10.1093/bioinformatics/btm467
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发表时间：
2007-12-15
期刊：
影响因子：
5.8
通讯作者：
McWeeney, Shannon
中科院分区：
文献类型：
--
作者：
Laderas, Ted;Bystrom, Cory;McWeeney, Shannon
考虑到输出格式的不兼容性，将定性蛋白质鉴定与定量蛋白质分析相结合并不是一件容易的事。我们介绍了TandTRAQ，这是一个独立的工具，它集成了i-Tracker的结果，i-Tracker是一个开源的iTRAQ量化程序，它的搜索结果来自开源蛋白质组搜索引擎XTandem。该实用程序从命令行运行，可以很容易地集成到管道中以实现自动化。
Integrating qualitative protein identification with quantitative protein analysis is non-trivial, given incompatibility in output formats. We present TandTRAQ, a standalone utility that integrates results from i-Tracker, an open-source iTRAQ quantitation program with the search results from XTandem, an open-source proteome search engine. The utility runs from the command-line and can be easily integrated into a pipeline for automation.