Flat Adenomas in the National Polyp Study: Is There Increased Risk for High-Grade Dysplasia Initially or During Surveillance?
Flat Adenomas in the National Polyp Study: Is There Increased Risk for High-Grade Dysplasia Initially or During Surveillance?
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DOI：
10.1016/s1542-3565(04)00392-1
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发表时间：
2004-10-01
影响因子：
12.6
通讯作者：
Schapiro, Melvin
中科院分区：
文献类型：
--
作者：
O'Brien, Michael J.;Winawer, Sidney J.;Schapiro, Melvin
背景与目的：平坦型腺瘤可能是结直肠癌发生中更具侵袭性的途径。来自国家息肉研究队列的固位性腺瘤在组织病理学上被重新分类为扁平或息肉样腺瘤，并与初始病理和监视病理进行比较。方法：对1980-1990年间发现的933例无柄腺瘤进行重新分类：(1)腺瘤厚度(AT)；
Background & Aims: The flat adenoma may be a more aggressive pathway in colorectal carcinogenesis. Sessile adenomas from the National Polyp Study cohort were reclassified histopathologically as flat or polypoid and compared with initial and surveillance pathology. Methods: A total of 933 sessile adenomas detected during 1980-1990 were reclassified as follows: (1) adenoma thickness (AT):