One-pot process to prepare 1,1,2,2-tetrafluoroindane from substituted 2,2-difluorostyrene and sodium chlorodifluoroacetate
One-pot process to prepare 1,1,2,2-tetrafluoroindane from substituted 2,2-difluorostyrene and sodium chlorodifluoroacetate
复制标题
DOI：
10.1016/j.tet.2006.10.041
复制
发表时间：
2007-01-01
期刊：
影响因子：
2.1
通讯作者：
Ke, Shun-Ying
中科院分区：
文献类型：
--
作者：
Lee, Chuan-Chen;Lin, Shaw-Tao;Ke, Shun-Ying
Reaction of 2,2-difluorostyrenes and sodium chlorodifluoroacetate in diglyme solution at 180 degrees C gave 1-aryl-2,2,3,3-tetrafluorocyclopropane as a primary product. After prolong reaction under the same condition, the 1, 1,2,2-tetrafluoroindanes can be isolated as the only product in good yields. All the tetrafluorocyclopropanes and tetrafluoroindanes were well characterized by spectroscopic analyses. (c) 2006 Elsevier Ltd. All rights reserved.
