Human Brucella canis outbreak linked to infection in dogs
Human Brucella canis outbreak linked to infection in dogs
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DOI：
10.1017/s0950268809990525
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发表时间：
2010-02-01
影响因子：
4.2
通讯作者：
Ayala, S. M.
中科院分区：
文献类型：
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作者：
Lucero, N. E.;Corazza, R.;Ayala, S. M.
对于在犬舍中处理繁殖犬或接触受感染动物的人来说，犬种布鲁氏菌的人畜共患风险被认为相当高。在其他情况下传播给人类被认为是罕见的。我们描述了一起由B引起的罕见布氏杆菌病爆发。犬，据我们所知，这是第一次在文献中报道。这次疫情涉及6人（3名儿童和3名成人）、1只母狗和3只小狗，它们每天都与该家庭密切接触。指示病例的临床症状导致了误诊，如果培养结果不是阳性，感染可能无法诊断。本报告旨在提高医务人员的认识，使他们认识到有必要对出现不明原因发热、不明原因脾或肝肿大或其他全身症状的儿童、免疫缺陷者或孕妇进行筛查。应评估这种疾病在城市地区新出现的人畜共患可能性以及协调犬布鲁氏菌病监测系统的必要性。
The zoonotic risk of Brucella canis has been considered fairly high for persons who handle breeding dogs in kennels or are exposed to infected animals. Transmission to humans in other circumstances has been thought to be rare. We describe an uncommon outbreak of brucellosis caused by B. canis which, to the best of our knowledge, is the first reported in the literature. This outbreak involved six persons (three children and three adults), a bitch and three puppies which had close daily contact with the family. The clinical symptoms of the index case led to an erroneous diagnosis and the infection would have gone undiagnosed if culture had not been positive. This report aims to increase awareness of medical personnel of the need to order screening tests for children, immunodeficient persons or pregnant women presenting with fever of unknown origin, unexplained spleen or liver enlargement or other systemic signs. The emerging zoonotic potential of this disease in urban areas and the need to coordinate canine brucellosis surveillance systems should be evaluated.