EVOLUTION OF RECOMBINATION IN A CONSTANT ENVIRONMENT
EVOLUTION OF RECOMBINATION IN A CONSTANT ENVIRONMENT
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DOI：
10.1073/pnas.77.8.4838
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发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
BROOKS, LD
中科院分区：
文献类型：
--
作者：
FELDMAN, MW;CHRISTIANSEN, FB;BROOKS, LD
The theory of evolution at a selectively neutral locus that controls the recombination between 2 major loci that are under selection is studied. If the major loci are at a stable equilibrium in linkage disequilibrium under selection and recombination, a mutation at the modifier locus will increase in frequency when rare if and only if it decreases the recombination fraction. If the major loci are in disequilibrium at a balance between selection against deleterious alleles and mutation towards them, 2 new phenomena are observed. A recombination increasing mutation will succeed if the disequilibrium is negative and the modifier is sufficiently tightly linked to the major loci. Depending on the strength of selection, even if the disequilibrium is negative, recombination reduction may occur for looser linkage between the major and modifier loci.
