Changes in prevalence of herpes simplex virus type 1 and 2 antibodies from 1973 to 1993 in the rural districts of Japan
Changes in prevalence of herpes simplex virus type 1 and 2 antibodies from 1973 to 1993 in the rural districts of Japan
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DOI：
10.1111/j.1348-0421.1999.tb02390.x
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发表时间：
1999-01-01
影响因子：
2.6
通讯作者：
Inouye, S
中科院分区：
文献类型：
--
作者：
Hashido, M;Kawana, T;Inouye, S
用GG-Capture ELISA法研究了1973年至1993年日本农村614份成人血清中HSV-1和HSV-2的血清阳性率的变化。男性和女性的HSV-1血清阳性率分别从1973年的75.3%和80.6%下降到1993年的54.4%和59.6%。HSV-2血清阳性率也从1973年的10.2%和9.9%下降到1993年的1.8%和1.2%。尽管HSV-2流行率的下降似乎与日本自20世纪50年代以来性传播疾病的普遍下降有关，但这些发现不应被解释为典型，因为根据性行为和队列，HSV-2感染在人群中的分布尤其不均匀。
Using the gG-capture ELISA, changes in the seroprevalence of: HSV-1 and HSV-2 from 1973 to 1993 were studied for 614 sera collected from general adults living in rural Japan. The HSV-1 seroprevalence for men and women decreased from 75.3 and 80.6% in 1973 to 54.4 and 59.6%, respectively, in 1993, The HSV-2 seroprevalence also decreased from 10.2 and 9.9% in 1973 to 1.8 and 1.2%, respectively, in 1993, Although the decrease in HSV-2 prevalence seemed to be correlated with the general decrease of sexually transmitted diseases in Japan since the 1950s, these findings should not be interpreted as typical, as HSV-2 infections are particularly known to distribute unevenly among populations, according to sexual activity and cohorts.