Risky decision making in Attention-Deficit/Hyperactivity Disorder: A meta-regression analysis
Risky decision making in Attention-Deficit/Hyperactivity Disorder: A meta-regression analysis
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DOI：
10.1016/j.cpr.2016.03.001
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发表时间：
2016-04-01
影响因子：
12.8
通讯作者：
Huizenga, Hilde M.
中科院分区：
文献类型：
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作者：
Dekkers, Tycho J.;Popma, Arne;Huizenga, Hilde M.
多动症与现实生活中各种形式的冒险决策有关，例如危险驾驶、不安全性行为和药物滥用。然而，关于ADHD患者决策缺陷的实验室研究结果并不一致，这可能是由于研究之间的差异。因此，我们进行了meta回归分析，纳入了37项研究（n ADHD = 1175; n Control = 1222），包含52个效应量。总体分析显示，效应大小为小到中等（标准化平均差= 0.36,p < 0.001, 95% CI）。22日。[51])，表明ADHD组比对照组表现出更多的风险决策。共病性破坏性行为障碍（DBD）有缓和影响的趋势：包括更多共病性破坏性行为障碍参与者的研究有更大的效应量。未发现共病内化障碍、年龄或任务明确性的调节作用。这些结果表明，ADHD与实验室环境中风险决策的增加有关，如果ADHD伴有DBD，这一点往往更为明显。因此，我们认为风险决策应该在ADHD的神经心理学和生物学机制研究中发挥更重要的作用，这对ADHD的评估和干预是有用的。(C) 2016 Elsevier Ltd.版权所有。
ADHD has been associated with various forms of risky real life decision making, for example risky driving, unsafe sex and substance abuse. However, results from laboratory studies on decision making deficits in ADHD have been inconsistent, probably because of between study differences. We therefore performed a meta-regression analysis in which 37 studies (n ADHD = 1175; n Control = 1222) were included, containing 52 effect sizes. The overall analysis yielded a small to medium effect size (standardized mean difference = .36, p < .001, 95% CI [.22, .51]), indicating that groups with ADHD showed more risky decision making than control groups. There was a trend fora moderating influence of co-morbid Disruptive Behavior Disorders (DBD): studies including more participants with co-morbid DBD had larger effect sizes. No moderating influence of co-morbid internalizing disorders, age or task explicitness was found. These results indicate that ADHD is related to increased risky decision making in laboratory settings, which tended to be more pronounced if ADHD is accompanied by DBD. We therefore argue that risky decision making should have a more prominent role in research on the neuropsychological and-biological mechanisms of ADHD, which can be useful in ADHD assessment and intervention. (C) 2016 Elsevier Ltd. All rights reserved.