THE EFFECT OF ARGON-LASER TRABECULOPLASTY UPON THE NORMAL HUMAN TRABECULAR MESHWORK
THE EFFECT OF ARGON-LASER TRABECULOPLASTY UPON THE NORMAL HUMAN TRABECULAR MESHWORK
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DOI：
10.1007/bf02169830
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发表时间：
1989-01-01
影响因子：
2.7
通讯作者：
CHURCH, WH
中科院分区：
文献类型：
--
作者：
ALEXANDER, RA;GRIERSON, I;CHURCH, WH
报道了通过扫描和透射电子显微镜测定的氩激光小梁成形术 (ALT) 对正常人体小梁网的影响。在摘除前 5 天和 1 天，眼睛的下鼻象限和颞象限分别接受 ALT 检测。激光撞击部位被确定为小梁的局灶性破坏，以及结缔组织和细胞碎片。激光损伤附近存活的小梁内皮细胞表现出吞噬和迁移活性的迹象。外源性巨噬细胞也有助于清除碎片。观察到活化的小梁细胞通过在角膜内皮上迁移而离开网状结构。 ALT 后 5 天，小梁细胞数量增加，但巨噬细胞数量减少。位于 Schwalbe 线附近的 Aa 激光损伤在 5 天内诱导局部角膜内皮波前向其前进，从而反映了我们看到的许多晚期失败的 ALT 样本。
The effect of argon laser trabeculoplasty (ALT) upon the normal human trabecular meshwork, as determined by scanning and transmission electron microscopy is reported. The lower nasal and temporal quadrants of an eye received ALT 5 and 1 day, respectively, prior to enucleation. Laser impact sites were identified as focal disruptions of trabeculae, together with connective tissue and cellular debris. Surviving trabecular endothelial cells near the laser lesions exhibited signs of phagocytic and migratory activity. Exogenous macrophages also contributed to the clearance of debris. Activated trabecular cells were observed leaving the meshwork by migrating over the corneal endothelium. By 5 days post-ALT increased amounts of trabecular cells but fewer macrophages were noted. Aa laser lesion sited close to the Schwalbe''s line induced, within 5 days, a local corneal endothelial wave front to advance towards it, thus reflecting many late failed ALT specimens that we have seen.