Response properties and functional organization of neurons in midline region of medullary reticular formation of cats.
Response properties and functional organization of neurons in midline region of medullary reticular formation of cats.
复制标题
猫髓质网状结构中线区神经元的反应特性和功能组织。
DOI：
10.1152/jn.1984.52.5.961
复制
发表时间：
1984
影响因子：
2.5
通讯作者：
P. Blum
中科院分区：
文献类型：
--
作者：
C. Yen;P. Blum
在麻醉猫的延髓中缝核和附近网状结构内的神经元进行细胞外单位记录。其中一些神经元的下行轴突在长度、传导速度和在脊髓白质中的位置方面具有特征。在躯体、压力感受器、视觉和听觉刺激后，对感觉特性进行了表征。延髓中缝核和大细胞被盖区神经元下行轴突的平均传导速度(26m/S)明显慢于其背侧各单位的平均传导速度(50m/S)。逆行刺激可诱发延髓中缝核和大细胞被盖区神经元的动作电位(30/43，70%)，而位于更背侧的中线和网状结构投射到腹柱的神经元(18/25，72%)。对身体表面的轻拍刺激最容易激活神经元。这种刺激激活了84%被测试的神经元。接受野很大，通常包括四肢、背部和头部。在所有被研究的区域都发现了TAP敏感神经元。毛发受体的刺激激活了37%的受试神经元，而19%的神经元对高强度的皮肤刺激(Pinch)有反应，35%的神经元对压力感受器刺激有反应，32%的神经元对视觉刺激有反应，33%的神经元对听觉刺激有反应。对挤压有反应的神经元可能对压力感受器刺激有反应，而不太可能对视觉刺激有反应。对视觉刺激有反应的神经元很可能对听觉刺激有反应。
Extracellular single-unit recordings were made in the anesthetized cat from neurons within the medullary raphe nuclei and nearby reticular formation. The descending axons from some of these neurons were characterized in terms of length, conduction velocity, and location within the white matter of the spinal cord. The sensory properties were characterized following somatic, baroreceptor, visual, and auditory stimuli. The mean conduction velocities of the descending axons from neurons in the medullary raphe nuclei and in the magnocellular tegmental field (26 m/s) were significantly slower than the mean conduction velocities of units in the regions immediately dorsal to them (50 m/s). Action potentials in neurons in the medullary raphe nuclei and in the magnocellular tegmental field were evoked by anti-dromic stimulation from the dorsolateral portion of the spinal cord (30 of 43, 70%), whereas neurons located in more dorsal regions along the midline and in the reticular formation projected into the ventral columns (18 of 25, 72%). Neurons were most easily activated by a tap stimulus to the body surface. This stimulus activated 84% of the neurons tested. The receptive fields were large, often including the four limbs, back, and head. Tap-sensitive neurons were found throughout the regions investigated. Stimulation of hair receptors activated 37% of neurons tested, whereas 19% responded to a high-intensity cutaneous stimulus (pinch), 35% responded to baroreceptor stimuli, 32% responded to visual stimuli, and 33% responded to auditory stimuli. Neurons responsive to pinch were likely to respond to baroreceptor stimuli and unlikely to respond to visual stimuli. Neurons responsive to visual stimuli were likely to respond to auditory stimuli.