TAPIR, a web server for the prediction of plant microRNA targets, including target mimics
TAPIR, a web server for the prediction of plant microRNA targets, including target mimics
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DOI：
10.1093/bioinformatics/btq233
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发表时间：
2010-06-15
期刊：
影响因子：
5.8
通讯作者：
Van de Peer, Yves
中科院分区：
文献类型：
--
作者：
Bonnet, Eric;He, Ying;Van de Peer, Yves
我们提出了一个新的Web服务器称为TAPIR，专为预测植物microRNA的目标。该服务器提供了使用快速和精确的算法搜索植物miRNA靶标的可能性。精确的选择要慢得多，但保证找到不太完美配对的miRNA靶双链体。此外，精确的选择允许预测靶标模拟物，其特征在于具有大环的miRNA-靶标双链体，使得它们无法通过传统工具检测。
We present a new web server called TAPIR, designed for the prediction of plant microRNA targets. The server offers the possibility to search for plant miRNA targets using a fast and a precise algorithm. The precise option is much slower but guarantees to find less perfectly paired miRNA-target duplexes. Furthermore, the precise option allows the prediction of target mimics, which are characterized by a miRNA-target duplex having a large loop, making them undetectable by traditional tools.