Relative contribution of lean and fat mass component to bone mineral density in males
Relative contribution of lean and fat mass component to bone mineral density in males
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DOI：
10.1007/s007740300003
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发表时间：
2003-01-01
影响因子：
3.3
通讯作者：
Nagata, Y
中科院分区：
文献类型：
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作者：
Douchi, T;Kuwahata, R;Nagata, Y
我们研究了93名健康日本男性志愿者（平均年龄，33.1 +/- 6.9岁;范围，18-54岁）的瘦体重（LBM）和体脂量对骨密度（BMD）的相对贡献。记录年龄、身高（Ht）、体重（Wt）和体重指数（BMI，Wt/Ht（2））。采用双能X线骨密度仪测量体脂质量、体脂百分比、体脂质量/Ht（2）、LBM、LBM/Wt、LBM/Ht（2）、腰椎（L2-L4）和全身骨密度（TBBMD）。在Pearson相关性检验中，LBM与L2-L4 BMD呈正相关。LBM、LBM/Wt、LBM/Ht（2）与TBBMD呈正相关。然而，体脂量和体脂量/Ht（2）与腰椎和全身BMD无关。在偏相关检验中，LBM与腰椎（r = 0.307，P < 0.05）和全身BMD（r = 0.545，P < 0.0001）仍相关，而体脂量与这些部位的BMD无关（r分别为-0.069和-0.169）。我们的结论是，在男性中，LBM是BMD的重要决定因素之一，而体脂量是一个可以忽略的BMD决定因素。
We investigated the relative contribution of lean body mass (LBM) and body fat mass to bone mineral density (BMD) in 93 healthy Japanese male volunteers (mean age, 33.1 +/- 6.9 years; range, 18-54 years). Age, height (Ht), weight (Wt), and body mass index (BMI, Wt/Ht(2)) were recorded. Body fat mass, percentage of body fat, body fat mass/Ht(2), LBM, LBM/Wt, LBM/Ht(2), and lumbar spine (L2-L4) and total body BMD (TBBMD) were measured by dual-energy X-ray absorptiometry. On the Pearson correlation test, LBM was positively correlated with L2-L4 BMD. LBM, LBM/Wt, and LBM/Ht(2) were positively correlated with TBBMD. However, body fat mass and body fat mass/Ht(2) were not correlated with lumbar spine and total body BMD. On the partial correlation test, LBM was still correlated with lumbar spine (r = 0.307, P < 0.05) and total body BMD (r = 0.545, P < 0.0001), irrespective of age and height, whereas body fat mass was not correlated with BMD of these sites (r = -0.069 and -0.169, respectively). We concluded that, in males, LBM is one of the significant determinants of BMD whereas body fat mass is a negligible BMD determinant.