Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease
Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease
复制标题
患有心肌疾病的胎儿在子宫内和出生后的特征和结果
DOI：
--
复制
发表时间：
2010
影响因子：
2.1
通讯作者：
L. Villa
中科院分区：
文献类型：
--
作者：
V. Fesslova;M. Mongiovì;S. Pipitone;J. Brankovic;L. Villa
目标. 91例胎儿扩张型或肥厚型心肌病（DCM，HCM）和心肌炎进行了研究。结果第1组“DCM”包括19只胎儿：13只水肿（FH）和5只相关心外畸形（ECA）（15.8%）。第2组“心肌炎”包括12只胎仔，其中11只患有FH。第3组“HCM”包括60个胎儿：26个有相关的ECA，17个有母体糖尿病，17个是“特发性”;然而，在一个病例中，出生后发现代谢紊乱，4个熟悉HCM。结果。10例选择终止妊娠。2例DCM和1例HCM失访。在已知随访情况下继续妊娠的病例中，第1组死亡率为68.75%，第2组为63.6%，第3组为31.3%（大多数为重度ECA）。存活的DCM和心肌炎病例改善，2例HCM恶化，6例保持稳定，26例改善或正常化。结论.我们的数据显示扩张型心肌病和心肌炎以及伴有严重相关ECA的患者预后更严重。
Objectives. Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied. Results. Group 1 “DCM” included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%). Group 2 “Myocarditis” included twelve fetuses, having 11 with FH. Group 3 “HCM” included sixty fetuses: 26 had associated ECAs, 17 had maternal diabetes, and 17 were “idiopathic”; however, in one case, a metabolic disorder was found postnatally, and 4 had familiarity for HCM. Outcomes. Ten cases opted for termination of pregnancy. Two cases with DCM and 1 with HCM were lost at follow-up. Out of the cases that continued pregnancy, with known follow-up, mortality was 68.75% in Group 1, 63.6% in Group 2, and 31.3% in Group 3 (the majority with severe ECAs). Surviving cases with DCM and myocarditis improved, 2 with HCM worsened, 6 remained stable, and 26 improved or normalized. Conclusions. Our data show more severe prognosis in DCM and myocarditis and forms with severe associated ECAs.
影响因子：
158.5
作者：
MICHELS, VV;MOLL, PP;TAZELAAR, HD
通讯作者：
TAZELAAR, HD