DYNAMICS OF LOCALIZED UNIMODAL PATTERNS IN REACTION-DIFFUSION SYSTEMS FOR CELL POLARIZATION BY EXTRACELLULAR SIGNALING
DYNAMICS OF LOCALIZED UNIMODAL PATTERNS IN REACTION-DIFFUSION SYSTEMS FOR CELL POLARIZATION BY EXTRACELLULAR SIGNALING
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DOI：
10.1137/18m1163749
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发表时间：
2018-01-01
影响因子：
1.9
通讯作者：
Ei, Shin-ichiro
中科院分区：
文献类型：
--
作者：
Kuwamura, Masataka;Seirin-Lee, Sungrim;Ei, Shin-ichiro
在本文中，我们研究了具有质量守恒的反应扩散系统中局部单峰斑图的动力学，这是细胞极性形成的数学模型。我们的研究结果提供了一个定量的精确表征的运动的本地化单峰模式，这表明，极性峰的位置可以确定普遍在一个网站，其中最大的细胞外信号是存在的，而不管的信号通路的细节。
In this paper, we study the dynamics of a localized unimodal pattern in reaction-diffusion systems with mass conservation, which are mathematical models for the polarity formation of cells. Our result provides a quantitatively precise characterization of the motion of the localized unimodal pattern, which suggests that the location of polarity peaks can be determined universally in a site where the maximal extracellular signal is present regardless of the details of the signaling pathways.