Contrast-enhanced ultrasound (CEUS) assessment of superselective uterine fibroid embolization (SUFE): Preliminary experience().
Contrast-enhanced ultrasound (CEUS) assessment of superselective uterine fibroid embolization (SUFE): Preliminary experience().
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DOI：
10.1016/j.jus.2008.09.005
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发表时间：
2008-12-01
影响因子：
2
通讯作者：
Serafini, G
中科院分区：
文献类型：
--
作者：
Sconfienza, L M;Lacelli, F;Serafini, G
目的：超选择性子宫肌瘤栓塞术(SUFE)的应用需要影像技术来验证手术的成功。本研究的目的是分析超声造影(CEUS)在治疗前后评估子宫肌瘤治疗结果和治疗后随访中的潜在价值。材料和方法：我们研究了12名接受子宫肌瘤超声治疗的妇女。在多发性肌瘤患者中，在本研究中只考虑了最大的三个。共检查21个病灶，大小3.5~9.0 cm，平均5.2 cm。每个肌瘤在SUFE之前和之后(当患者还在血管造影室时)立即进行检查，并在静脉注射单剂造影剂后进行经腹CEU。随访方案包括治疗后1个月的CEUS评估和治疗6个月后的CEUS加动态磁共振(MR)检查。结果：在20/21例患者中，栓塞术后的CEUS显示肌瘤完全断流。其余病变(1例女性多发性病变)在SUFE后显示持续的血管形成。这些发现都与血管造影数据相一致。在六个月的随访期内未见复发。1例患者在SUFE术后18个月再次出现症状，CEUS显示病变内血管持续存在。结论：CEUS是评估子宫肌瘤SUFE术后血管闭塞完整性的有效方法。CEUS结果与治疗后1个月和6个月观察的临床结果相关。与动态MR相比，CEU具有可靠性高、成本低等优点。
PURPOSE: The use of superselective uterine fibroid embolization (SUFE) requires imaging techniques that can be used to verify the success of the procedure. The purpose of our study was to analyze the potential value of pre- and post-treatment contrast-enhanced ultrasonography (CEUS) for assessing the outcome of SUFE and for posttreatment follow-up.MATERIALS AND METHODS: We studied twelve women undergoing SUFE for uterine fibroids. In those with multiple fibroids, only the three largest were considered in this study. A total of 21 lesions (size range 3.5-9.0cm, mean 5.2cm) were examined. Each myoma was examined immediately before and after SUFE (while the patient was still in the angiography room) with transabdominal CEUS performed after intravenous administration of a single bolus of contrast agent. The follow-up protocol included CEUS evaluation one month after treatment and CEUS plus dynamic magnetic resonance (MR) studies six months after treatment.RESULTS: In 20/21 cases, postembolization CEUS revealed total fibroid devascularization. The remaining lesion (in a woman with multiple lesions) showed persistent vascularization after SUFE. These findings were all consistent with angiographic data. No recurrences were observed during the six-month follow-up. One patient reported the reappearance of symptoms 18 months after SUFE, and CEUS showed the persistence of intralesional vascularization.CONCLUSIONS: CEUS is effective for assessing the completeness of vascular occlusion following SUFE for uterine fibroids. CEUS findings correlate with clinical results observed one and six months after treatment. Compared with dynamic MR, CEUS is reliable and cost-effective.