Radiofrequency hyperthermia for clinical cancer therapy.
Radiofrequency hyperthermia for clinical cancer therapy.
复制标题
射频热疗用于临床癌症治疗。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
Antich Pp
中科院分区：
文献类型：
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作者：
Kim Jh;Hahn Ew;Antich Pp
通过感应或电容方式的射频加热有可能引起深度热疗。利用多通道电极和阻抗匹配的电容加热技术的进展显示出改善加热深度的希望。然而，脂肪组织的加热仍然是一个主要障碍。感应方式已广泛用于透热治疗，一种改进的装置正在用于治疗浅表肿瘤。诱导模式受组织不均匀性的影响最小，在深部肿瘤的加热中具有很大的应用前景。使用射频加热，肿瘤和邻近正常组织之间的温度测量几乎总是显示出选择性加热模式。肿瘤对高温的单独反应是短暂的；然而，在不增加正常组织并发症的情况下，如果与照射联合使用，可以达到75%以上的永久性控制。
Radiofrequency heating by the inductive or capacitive mode has the potential to induce hyperthermia at depth. Progress with the capacitive heating with the use of multiportal electrodes and impedance matching showed promise for improved depth of heating. However, heating of the fatty tissue remains a major obstacle. The inductive modality has been widely used for diathermy, and a modified unit is being used for treatment of superficial tumors. The inductive mode has great promise for heating deep-seated tumors because it is least affected by the tissue inhomogeneities. With radiofrequency heating, temperature measurements between the tumor and the adjacent normal tissue almost always showed a selective heating pattern. Tumor response to the heat alone has been transitory; however, permanent control can be achieved in over 75% when combined with irradiation without an increase in normal tissue complications.