Individual Cerebral Hemodynamic Response to Caffeine Was Related to Performance on a Newly Developed Stroop Color-Word Task
Individual Cerebral Hemodynamic Response to Caffeine Was Related to Performance on a Newly Developed Stroop Color-Word Task
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DOI：
10.1007/s10043-003-0607-5
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发表时间：
2003-12
期刊：
影响因子：
1.2
通讯作者：
T. Niioka;M. Sasaki
中科院分区：
文献类型：
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作者：
T. Niioka;M. Sasaki
一项改良的Stroop颜色词任务已经被开发出来，作为一项认知任务来激活前额叶皮层，并试图澄清摄入咖啡因后脑血流动力学的变化是否与年轻男性受试者在改良Stroop任务中的表现变化有关。在这个修改后的任务中，受试者被要求快速选择计算机屏幕上的彩色磁盘，以响应每次试验同时呈现一个颜色单词的指令，即“颜色”或“意义”。呈现的颜色词的颜色与这个词的意思不一致。使用连续波近红外光谱无创测量前额叶联合皮层血容量和氧合的相对变化。结果表明，咖啡因的摄入降低了改良Stroop任务中大脑的血容量和氧合血红蛋白浓度，而后者的个体变化与咖啡因摄入后任务表现的变化有关。
A modified Stroop color-word task has been developed to activate the prefrontal cortex as a cognitive task and it has been tried to clarify whether change in the cerebral hemodynamics after ingesting caffeine is associated with change in performance on the modified Stroop task in young male subjects. In this modified task, subjects were instructed to quickly select a colored disk on a computer screen in response to an instruction, i.e. “color” or “meaning”, presented simultaneously with one color word at each trial. The color of the presented color word was discordant with the meaning of the word. Relative changes in blood volume and oxygenation in the prefrontal association cortex were measured noninvasively using continuous-wave near-infrared spectroscopy. The results showed that caffeine ingestion decreased blood volume and oxygenated hemoglobin concentration in the brain during the modified Stroop task, and that the individual change in the latter was related to change in performance on the task following caffeine ingestion.