Cardiac structural and functional changes in old elderly patients with obstructive sleep apnoea–hypopnoea syndrome
Cardiac structural and functional changes in old elderly patients with obstructive sleep apnoea–hypopnoea syndrome
复制标题
老年阻塞性睡眠呼吸暂停低通气综合征患者心脏结构和功能的变化
DOI：
10.1177/0300060513502890
复制
发表时间：
2014
影响因子：
1.6
通讯作者：
Yan
中科院分区：
文献类型：
--
作者：
Yi Sun;H. Yuan;Miao;Yan Wang;M. Xia;Yan
目的探讨老年阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者心脏结构的变化及其对左心室收缩、舒张功能的影响。方法 该研究纳入了老年 OSAHS 患者和年龄匹配的健康对照受试者。使用多普勒超声扫描仪测量心脏结构、左心室舒张功能和左心室收缩功能，并比较两组之间的情况。结果该研究包括 136 名 OSAHS 患者和 50 名健康对照受试者。两组间反映心脏结构的超声心动图指标，包括室间隔、左心室后壁厚度、左心室质量及质量指数存在显着差异。两组室间隔舒张早期心肌峰值速度/舒张末期心肌峰值速度(Em/Am)、二尖瓣环Em/Am、左心室后壁Em/Am差异有统计学意义。两组室间隔、二尖瓣环、左心室后壁收缩期峰值速度等指标也存在显着差异。结论老年OSAHS患者心脏结构发生改变，左心室舒张、收缩功能明显减退。
Objective To investigate cardiac structural changes in elderly patients with obstructive sleep apnoea–hypopnoea syndrome (OSAHS) and the impact on left ventricular systolic and diastolic function. Methods The study enrolled elderly patients with OSAHS and age-matched healthy control subjects. Cardiac structure, left ventricular diastolic function and left ventricular systolic function were measured using a Doppler ultrasound scanner and compared between the two groups. Results The study included 136 patients with OSAHS and 50 healthy control subjects. There were significant differences in the echocardiography indicators that reflect cardiac structure, including interventricular septum, left ventricle posterior wall thickness, and left ventricular mass and mass index between the two groups. There were significant differences between the two groups in the ventricular septal early diastolic myocardial peak velocity/late diastolic myocardial peak velocity (Em/Am), mitral annulus Em/Am, and left ventricle posterior wall Em/Am. There were also significant differences in the indicators of interventricular septum, mitral annulus and left ventricular posterior wall systolic peak velocity between the two groups. Conclusion Elderly patients with OSAHS demonstrated cardiac structural changes and their left ventricular diastolic and systolic functions were significantly diminished.
DOI：
10.1016/j.beem.2010.08.011
发表时间：
2010-10
期刊：
Best practice & research. Clinical endocrinology & metabolism
影响因子：
--
作者：
Drager LF;Jun JC;Polotsky VY
通讯作者：
Polotsky VY
影响因子：
9.6
作者：
Lancaster, Lisa H.;Mason, Wendi R.;Malow, Beth A.
通讯作者：
Malow, Beth A.