Sulcal organization in the medial frontal cortex provides insights into primate brain evolution
Sulcal organization in the medial frontal cortex provides insights into primate brain evolution
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DOI：
10.1038/s41467-019-11347-x
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发表时间：
2019-07-31
影响因子：
16.6
通讯作者：
Petrides, Michael
中科院分区：
文献类型：
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作者：
Amiez, Celine;Sallet, Jerome;Petrides, Michael
虽然在灵长类进化中额叶皮层的相对扩张被普遍接受，但人类独特性的本质（如果有的话）以及额叶区域的物种间解剖功能比较仍然存在争议。为了提供一个新的解释灵长类动物大脑的进化，脑沟内侧额叶皮层的形态变异性进行了评估，在旧大陆猴（猕猴/狒狒）和Hominoidea（黑猩猩/人）。我们发现，这两个Hominoidea拥有一个副扣带沟，这是以前被认为是人类大脑所独有的，并与更高的认知功能，如心智化。此外，我们显示了系统的脑沟形态组织的内侧额叶皮质，可以追溯到旧大陆的猴子Hominoidea物种，表现出进化保守的组织原则。这些数据提供了一个新的框架，比较脑沟形态，cytoarchitectonic面积分布，连通性和功能的灵长类动物的顺序，导致明确的预测其他灵长类动物的大脑可能是解剖功能组织。
Although the relative expansion of the frontal cortex in primate evolution is generally accepted, the nature of the human uniqueness, if any, and between-species anatomo-functional comparisons of the frontal areas remain controversial. To provide a novel interpretation of the evolution of primate brains, sulcal morphological variability of the medial frontal cortex was assessed in Old World monkeys (macaque/baboon) and Hominoidea (chimpanzee/human). We show that both Hominoidea possess a paracingulate sulcus, which was previously thought to be unique to the human brain and linked to higher cognitive functions, such as mentalizing. Also, we show systematic sulcal morphological organization of the medial frontal cortex that can be traced from Old World monkeys to Hominoidea species, demonstrating an evolutionarily conserved organizational principle. These data provide a new framework to compare sulcal morphology, cytoarchitectonic areal distribution, connectivity, and function across the primate order, leading to clear predictions about how other primate brains might be anatomo-functionally organized.