Dynamic prediction of relapse in patients with acute leukemias after allogeneic transplantation: Joint model for minimal residual disease
Dynamic prediction of relapse in patients with acute leukemias after allogeneic transplantation: Joint model for minimal residual disease
复制标题
急性白血病同种异体移植后复发的动态预测：微小残留病联合模型
DOI：
10.1111/ijlh.13328
复制
发表时间：
2020-09-03
影响因子：
3
通讯作者：
Hu, Xiaoxia
中科院分区：
文献类型：
--
作者：
Huang, Aijie;Chen, Qi;Hu, Xiaoxia
复发仍然是白血病异基因造血干细胞移植（alloHSCT）后治疗失败的主要原因。大量研究表明，alloHSCT 之前或之后的微小残留病 (MRD) 可以预测复发风险。这些MRD数据是在特定检查点收集的，无法动态预测alloHSCT后的复发风险，需要进行连续监测。
Relapse remains the leading cause of treatment failure after allogeneic hematopoietic stem cell transplantation (alloHSCT) in leukemia. Numerous investigations have demonstrated that minimal residual disease (MRD) before or after alloHSCT is prognostic of relapse risk. These MRD data were collected at specific checkpoints and could not dynamically predict the relapse risk after alloHSCT, which needs serial monitoring.