The effects of the music-with-movement intervention on the cognitive functions of people with moderate dementia: a randomized controlled trial
The effects of the music-with-movement intervention on the cognitive functions of people with moderate dementia: a randomized controlled trial
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DOI：
10.1080/13607863.2016.1251571
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发表时间：
2018-01-01
影响因子：
3.4
通讯作者：
Leung, Mason Chin Pang
中科院分区：
文献类型：
--
作者：
Cheung, Daphne Sze Ki;Lai, Claudia Kam Yuk;Leung, Mason Chin Pang
目的：本研究的目的是探讨为期六周的音乐运动（MM）干预与听音乐（ML）和社交活动（SA）相比，对中度痴呆患者认知功能随时间的影响。方法：对 165 名中度痴呆疗养院居民进行了一项多中心随机对照试验。 MM 干预方案是根据批判性文献综述制定的，并在本研究中进行测试之前经过三轮试点研究的测试。参与者被随机分为三组。干预参与者 (n = 58) 接受了由训练有素的医疗保健专业人员领导的为期 12 周的 MM 计划，而对比 ML 组的参与者 (n = 54) 则听他们喜欢的音乐，而 SA 组的参与者 (n = 53) 则参与社交聊天。在基线、第六周和干预后六周测量认知功能、抑郁症状和焦虑。结果：单变量分析和配对比较显示，MM 组的记忆力和抑郁症状有更大改善。对记忆的影响在干预后可能会持续至少六周。然而，混合多变量方差分析 (MANOVA) 分析表明，时间效应之间不存在显着的交互作用结论：研究结果表明，MM 干预可能有助于增强痴呆症患者的认知功能。然而，没有足够的证据表明 MM 干预对结果变量随时间的影响与对照组中观察到的显着不同。
Objective: The aim of this study was to examine the effects of the six-week music-with-movement (MM) intervention, as compared with music listening (ML) and social activity (SA), on the cognitive functions of people with moderate dementia over time.Methods: A multi-center randomized controlled trial was conducted on 165 nursing home residents with moderate dementia. The MM intervention protocol was developed based on a critical literature review, and tested in three rounds of pilot studies before undergoing testing in this study. The participants were randomly allocated into three groups. Intervention participants (n = 58) received a 12-week MM program led by a trained health care professional, while the participants in the comparison ML group (n = 54) listened to their preferred music, and those in the SA group (n = 53) engaged in social chatting. Cognitive functions, depressive symptoms, and anxiety were measured at baseline, the sixth week, and six weeks post-intervention.Results: Greater improvements in memory and depressive symptoms for the MM group were revealed in the univariate analysis and pairwise comparisons. The effects on memory could last for at least six weeks post-intervention. However, a mixed multivariate analysis of variance (MANOVA) analysis indicated that there were no significant interactions of group by time effectConclusion: The findings revealed that the MM intervention may be useful for enhancing the cognitive functions of people with dementia. However, there is insufficient evidence to show that the effects of the MM intervention on outcome variables over time significantly different from those observed among the comparison groups.