Pattern of antidepressant use and duration of depression-related absence from work
Pattern of antidepressant use and duration of depression-related absence from work
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DOI：
10.1192/bjp.183.6.507
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发表时间：
2003-12-01
影响因子：
10.5
通讯作者：
Goering, P
中科院分区：
文献类型：
--
作者：
Dewa, CS;Hoch, JS;Goering, P
背景：很少有研究探讨抗抑郁药处方与获得抑郁症相关残疾福利之间的关系。目的解决两个问题：第一，按照已公布的临床指南处方抗抑郁药是否与更好的残疾结局相关；第二，符合指南的抗抑郁药处方与残疾时间有什么关系？方法利用加拿大三家主要金融和保险公司的管理数据进行观察性研究。结果推荐的一线制剂和推荐剂量与重返工作岗位显著相关(X(2)=6.64P<；0.036)。此外，在重返工作岗位的人中，早期干预与残疾发作的缩短显著相关(β=-24.1：95%CI-34.4至-13.8)。结论抑郁相关的工作场所残疾是一个没有简单解决方案的问题。这些结果为帮助因抑郁症而残疾的工人重返工作岗位的难题提供了额外的一块。利益声明没有。
Background Few studies have examined the relationship between antidepressant prescription and receipt of depression-related disability benefits.Aims To address two questions: first, is prescription of antidepressants in accordance with published clinical guides associated with better disability outcomes, and second, what is the relationship between guideline-concordant antidepressant prescription and length of disability?Method An observational study was conducted using administrative data from three major Canadian financial and insurance sector companies. Short-term disability and prescription drug claims records for 1996-1998 were linked for workers receiving depression-related short-term disability benefits during that time.Results Recommended first-line agents and recommended doses were significantly associated with return to work (chi(2)=6.64, P < 0.036). In addition, among those who returned to work, early intervention was significantly associated with a shortened disability episode (beta = -24.1: 95% Cl -34.4 to -13.8).Conclusions Depression-related workplace disability is a problem for which there is no simple solution. These results provide an additional piece to the puzzle of helping workers disabled by depression to return to work.Declaration of interest None.