Cup-to-vesicle transition of a fluid membrane with spontaneous curvature
Cup-to-vesicle transition of a fluid membrane with spontaneous curvature
复制标题
DOI：
10.1063/1.5113646
复制
发表时间：
2019-09-07
影响因子：
4.4
通讯作者：
Noguchi, Hiroshi
中科院分区：
文献类型：
--
作者：
Noguchi, Hiroshi
不具有自发曲率的流体膜的盘到囊泡的转变可以通过边缘线和曲率能量之间的竞争来很好地描述。然而，具有自发曲率的不对称膜的转变尚不清楚。在这项研究中，利用理论和无网格膜模拟研究了具有恒定自发曲率的流体膜片的形状及其向囊泡的闭合过渡。已证实（亚）稳定膜和瞬态膜与球盖非常接近。膜高斯模量可以根据膜片的杯形以及转移概率来估计，尽管后者的估计给出稍小的负值。此外，还提出了膜的自组装动力学，其中较小的囊泡在较高的自发曲率、较高的边缘线张力和较低的密度下形成。
The disk-to-vesicle transition of a fluid membrane with no spontaneous curvature is well described by the competition between edge line and curvature energies. However, the transition of asymmetric membranes with spontaneous curvatures is not yet understood. In this study, the shape of the fluid membrane patch with a constant spontaneous curvature and its closing transition to a vesicle is investigated using theory and meshless membrane simulations. It is confirmed that the (meta)stable and transient membranes are well approximated by spherical caps. The membrane Gaussian modulus can be estimated from the cup shape of membrane patches as well as from the transition probability, although the latter estimate gives slightly smaller negative values. Furthermore, the self-assembly dynamics of membranes are presented, in which smaller vesicles are formed at higher spontaneous curvatures, higher edge line tension, and lower density.