STUDIES IN RELATION TO BIOSYNTHESIS .46. INCORPORATION OF CYCLO-L-TRYPTOPHYL-L-PROLINE INTO BREVIANAMIDE A
STUDIES IN RELATION TO BIOSYNTHESIS .46. INCORPORATION OF CYCLO-L-TRYPTOPHYL-L-PROLINE INTO BREVIANAMIDE A
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DOI：
10.1039/p19740000050
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发表时间：
1974-01-01
期刊：
影响因子：
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通讯作者：
RUSSELL, RA
中科院分区：
文献类型：
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作者：
BALDAS, J;BIRCH, AJ;RUSSELL, RA
对短密青霉中短青霉酰胺A（1）的培养条件和分离方法进行了改进。使用3 H和14 C标记已经表明，环-L-羟乙基-L-脯氨酸（5）被有效地掺入短藤酰胺A（1）中，并提出了生物合成序列。
The culture conditions and method of isolation of brevianamide A (1) from Penicillium brevicompactum have been improved. Use of 3H and 14C labelling has shown that cyclo-L-tryptophyl-L-proline (5) is incorporated efficiently into brevianamide A (1) and a biosynthetic sequence is proposed.