Japanese Encephalitis in Travelers from Non-Endemic Countries, 1973-2008
Japanese Encephalitis in Travelers from Non-Endemic Countries, 1973-2008
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DOI：
10.4269/ajtmh.2010.09-0676
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发表时间：
2010-05-01
影响因子：
3.3
通讯作者：
Fischer, Marc
中科院分区：
文献类型：
--
作者：
Hills, Susan L.;Griggs, Anne C.;Fischer, Marc
日本脑炎（JE）是一种严重的疾病，对访问流行国家的旅行者来说是一种风险。我们回顾了从1973年到2008年来自非流行地区的旅行者中所有已发表的乙脑病例，并评估了与感染风险相关的因素。有55例病例发生在17个国家的公民中。病例患者年龄范围为1-91岁（中位数= 34岁），10人（18%）死亡，24人（44%）有轻度至重度后遗症。在对37例患者进行的详细风险评估中，24例（65%）曾在乙脑流行地区生活≥ 1个月，大多数患者存在可能增加感染风险的因素。总体乙脑风险的估计值较低，
Japanese encephalitis (JE) is a severe disease and a risk for travelers who visit JE-endemic countries. We reviewed all published JE cases in travelers from non-endemic areas from 1973 through 2008, and assessed factors related to risk of infection. There were 55 cases that occurred in citizens of 17 countries. Age range of case-patients was 1-91 years (median = 34 years).Ten (18%) persons died and 24 (44%) had mild to severe sequelae. In a detailed risk assessment of 37 case-patients, 24 (65%) had spent >= 1 month in JE-endemic areas, and most had factors identified that may have increased infection risk. The estimate of overall JE risk was low,