In vivo femoropopliteal arterial wall compliance in subjects with and without lower limb vascular disease
In vivo femoropopliteal arterial wall compliance in subjects with and without lower limb vascular disease
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DOI：
10.1016/s0741-5214(99)70020-0
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发表时间：
1999-11-01
影响因子：
4.3
通讯作者：
Hamilton, G
中科院分区：
文献类型：
--
作者：
Tai, NRM;Giudiceandrea, A;Hamilton, G
目的：本研究的目的是进一步发展的顺应性血管移植物的股腘动脉的弹性性能的初步评估，在受试者与无loner肢体外周血管diseases.Methods：这一前瞻性对照研究设置在一所大学的外科系。使用超声扫描血管壁跟踪系统，同时测量肱动脉血压，测量股腘动脉壁运动，在11例外周血管疾病患者（第1组），在11名年龄较大的对照组，血压，年龄和性别相匹配（第2组），并在12名年轻的对照组（第3组）。测定股总动脉、近端股浅动脉、远端股浅动脉（DSPA）和膝中腘动脉的直径顺应性和刚度指数。组1中的所有动脉节段均显示出比组2（年龄匹配的对照血管）增加刚度和降低顺应性的趋势，股总动脉的扩张性明显较低（平均顺应性分别为6.2%和14.1% mm Hg-1 x 10（-2）; P
Objective: The purpose of this study was to further the development of a compliant vascular graft with a preliminary assessment of the elastic properties of the femoropopliteal artery in subjects with and without loner limb peripheral vascular disease.Methods: This prospective controlled study was set in a university department of surgery. Using an ultrasound scan wall tracking system with the simultaneous measurement of brachial blood pressure, measurements of femoropopliteal artery wall motion were undertaken in 11 patients with peripheral vascular disease (group 1), in 11 older control subjects who were matched for blood pressure, age, and sex (group 2), and in 12 younger control subjects (group 3). Diametrical compliance and stiffness index were determined for the common femoral artery, the proximal superficial femoral artery, the distal superficial femoral artery (DSPA), and the midgenicular popliteal artery.Results: All the arterial segments in group 1 showed a trend towards increased stiffness and less compliance than the group 2, age-matched control vessels, with significantly lower distensibility noted at the common femoral artery (mean compliance of 6.2% vs 14.1% mm Hg-1 x 10(-2), respectively; P