Liver volume variation in patients with virus-induced cirrhosis: Findings on MDCT
Liver volume variation in patients with virus-induced cirrhosis: Findings on MDCT
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DOI：
10.2214/ajr.07.2181
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发表时间：
2007-09-01
影响因子：
5
通讯作者：
Chen, Xin-Zu
中科院分区：
文献类型：
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作者：
Zhou, Xiang-Ping;Lu, Tao;Chen, Xin-Zu
OBJECTIVE.本研究的目的是建立一个标准的肝脏体积公式，并探讨病毒性肝硬化患者的肝叶变异和疾病的严重程度之间的相关性，通过测量全肝，左外侧段，尾状叶使用16-MDCT。材料和方法。对113例正常肝脏和101例病毒性肝硬化患者行容积CT扫描，计算全肝、肝左外侧段和肝尾状叶的体积和单位体表面积（BSA）体积。计算肝左外段体积、尾状叶体积占肝总体积的比例、体积指数、体积变化率，并按Child-Pugh分级进行分组比较。根据体重和身高或BSA. SDS构建标准肝脏体积公式。肝脏体积（LV）与身高、体重（BW）[ LV（cm（3））= 12.90 x BW（kg）+ 437.91]和BSA [ LV（cm（3））= 882.08 x BSA（m2）- 308.12]呈正相关。对照组的总平均值+/-标准误（SE）肝脏体积为1，222.76 +/- 216.96 cm（3）。Child-Pugh C级患者的整个肝脏和左外侧段的平均体积分别为798.01 +/- 203.64和213.04 +/- 74.84 cm（3），显著小于Child-Pugh A级和B级患者的数值（p < 0.05）。Child-Pugh A级患者的尾状叶平均体积为36.83 ± 22.11 cm（3），显著大于Child-Pugh B和C级患者（p < 0.05）。CT测量的肝脏体积和标准肝脏体积公式有助于评估肝脏体积的变化。Child-Pugh A级和B级患者左外侧段扩大是绝对的，而Child-Pugh C级患者是相对的; Child-Pugh A级患者尾状叶扩大是绝对的，而Child-Pugh B级和C级患者是相对的。
OBJECTIVE. The objective of our study was to establish a standard liver volume formula and explore the correlation between hepatic lobe variations in patients with virus-induced cirrhosis and the severity of disease by measuring the volume of the whole liver, the left lateral segment, and the caudate lobe using 16-MDCT.MATERIALS AND METHODS. The volume and per-body surface area ( BSA) volume of the whole liver, the left lateral segment, and the caudate lobe were calculated in 113 patients with normal livers and 101 patients with virus-induced cirrhosis who underwent volume CT. The proportion of the left lateral segment volume and the proportion of the caudate lobe volume to the total liver volume, the volume index, and the volume change ratio were also calculated, and these data were grouped by Child-Pugh classification and compared. The standard liver volume formula was constructed from body weight and body height or from BSA.RESULTS. There was a positive correlation between liver volume ( LV) and body height, body weight ( BW) [ LV ( cm(3)) = 12.90 x BW ( kg) + 437.91], and BSA [ LV ( cm(3)) = 882.08 x BSA ( m(2)) - 308.12]. The total mean +/- standard error ( SE) liver volume of the control group was 1,222.76 +/- 216.96 cm(3). The mean volumes of the whole liver and of the left lateral segment were 798.01 +/- 203.64 and 213.04 +/- 74.84 cm(3), respectively, for Child-Pugh class C patients, which was significantly smaller than those values for Child-Pugh class A and B patients ( p < 0.05). The mean volume of the caudate lobe was 36.83 +/- 22.11 cm(3) for Child-Pugh class A patients, which is significantly larger than those values for Child-Pugh class B and C patients ( p < 0.05).CONCLUSION. CT-measured liver volume and standard liver volume formulas were helpful in evaluating liver volume variations. Enlargement of the left lateral segment was absolute in Child-Pugh class A and B patients, but was relative in Child-Pugh class C patients; enlargement of the caudate lobe was absolute in Child-Pugh class A patients, but was relative in Child-Pugh class B and C patients.