Zeaamine, a new amine from roots of Zea mays and its cytotoxic activity against CT26 and SW480 cell lines.
Zeaamine, a new amine from roots of Zea mays and its cytotoxic activity against CT26 and SW480 cell lines.
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DOI：
10.1080/14786419.2023.2290149
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发表时间：
2023-12
影响因子：
2.2
通讯作者：
Yunqiang Zhang;Weiguo Chen;Yiling Zhang;Xue Qiu;Yanhua Fan;Jianyu Liu;Andong Wang;Yongnan Xu
中科院分区：
文献类型：
--
作者：
Yunqiang Zhang;Weiguo Chen;Yiling Zhang;Xue Qiu;Yanhua Fan;Jianyu Liu;Andong Wang;Yongnan Xu
从玉米根中分离得到一个新的胺类化合物，命名为玉米胺（1），沿着分离得到9个已知化合物（2-10）。其中化合物2为首次从该植物中分离得到，化合物3为首次从该植物根中分离得到。在本研究中，评价了化合物对CT 26和SW 480细胞的细胞毒性。玉米胺（1）对CT 26和SW 480细胞表现出中度影响，IC 50值为17.91和10.21 µM。
A new amine, zeaamine (1), along with nine known compounds (2-10), were isolated from the roots of Zea mays. Among these, compound 2 was first isolated from this plant, and compound 3 was first isolated from the roots. In the current investigation, the cytotoxicity against CT26 and SW480 cells of the compounds were evaluated. Zeaamine (1) exhibited moderately affected CT26 and SW480 cells with IC50 values of 17.91 and 10.21 µM.