Dynamic Contrast-Enhanced Breast MRI at 7 Tesla Utilizing a Single-loop Coil: A Feasibility Trial
Dynamic Contrast-Enhanced Breast MRI at 7 Tesla Utilizing a Single-loop Coil: A Feasibility Trial
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DOI：
10.1016/j.acra.2010.03.017
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发表时间：
2010-08-01
影响因子：
4.8
通讯作者：
Lauenstein, Thomas C.
中科院分区：
文献类型：
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作者：
Umutlu, Lale;Maderwald, Stefan;Lauenstein, Thomas C.
基本原理和目标：本研究的目的是评估动态对比增强超高场乳腺成像在7 Tesla.Material和方法的可行性：共15名受试者，其中包括5例经组织学证实的乳腺癌患者，进行了检查7特斯拉全身磁共振成像系统使用单边线性极化单回路线圈。受试者以俯卧位放置在活检支撑系统上，线圈直接放置在感兴趣区域下方。检查方案包括以下序列：1）T2加权快速自旋回波序列; 2）6个动态T1加权扰相梯度回波序列;和3）减影imaging.Results：对比增强T1加权成像在7特斯拉可以获得高空间分辨率，采集时间短，提供了良好的图像准确性和一个明确的良好描绘小的解剖和病理结构。T2加权成像可以在适当的采集时间获得高空间分辨率。由于线圈的限制，四个高场磁共振检查显示诊断value.Conclusions下降：这第一次科学的方法动态对比增强乳腺磁共振成像在7特斯拉演示了超高场乳腺磁共振成像的复杂性和countenances进一步先进的双边线圈的概念，以规避线圈和超高场磁场强度的电流限制的实施。
Rationale and Objectives: The aim of this study was to assess the feasibility of dynamic contrast-enhanced ultra-high-field breast imaging at 7 Tesla.Material and Methods: A total of 15 subjects, including 5 patients with histologically proven breast cancer, were examined on a 7 Tesla whole-body magnetic resonance imaging system using a unilateral linearly polarized single-loop coil. Subjects were placed in prone position on a biopsy support system, with the coil placed directly below the region of interest. The examination protocol included the following sequences: 1) T2-weighted turbo spin echo sequence; 2) six dynamic T1-weighted spoiled gradient-echo sequences; and 3) subtraction imaging.Results: Contrast-enhanced T1-weighted imaging at 7 Tesla could be obtained at high spatial resolution with short acquisition times, providing good image accuracy and a conclusively good delineation of small anatomical and pathological structures. T2-weighted imaging could be obtained with high spatial resolution at adequate acquisition times. Because of coil limitations, four high-field magnetic resonance examinations showed decreased diagnostic value.Conclusions: This first scientific approach of dynamic contrast-enhanced breast magnetic resonance imaging at 7 Tesla demonstrates the complexity of ultra-high-field breast magnetic resonance imaging and countenances the implementation of further advanced bilateral coil concepts to circumvent current limitations from the coil and ultra-high-field magnetic strength.