Antifungal activity against Candida species of the selective serotonin-reuptake inhibitor, sertraline

Antifungal activity against Candida species of the selective serotonin-reuptake inhibitor, sertraline
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DOI:
10.1086/324589
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发表时间:
2001-12-15
影响因子:
11.8
通讯作者:
Ledochowski, M
Ledochowski, M
中科院分区:
医学1区
文献类型:
--
作者:
Lass-Flörl, C;Dierich, MP;Ledochowski, M

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3例经前焦虑症(PMDD)和复发性外阴阴道念珠菌病(VVC)患者接受了舍曲林(Tresleen,选择性5-羟色胺再摄取抑制剂;辉瑞)治疗PMDD。在舍曲林干预期间,患者没有急性VVC复发。观察了舍曲林对各种念珠菌分离株的抗真菌活性。
Three patients with premenstrual dysphoric disorder (PMDD) and recurrent vulvovaginal candidiasis (VVC) underwent sertraline therapy (Tresleen, a selective serotonin-reuptake inhibitor; Pfizer) for PMDD. During sertraline intervention, patients had no recurrent episodes of acute VVC. Antifungal activity was observed for sertraline against various isolates of Candida species.