THE REMARKABLE EFFECT OF ZNCL2 AN ASYMMETRIC ENOLIZATION REACTIONS OF CHIRAL BASES
THE REMARKABLE EFFECT OF ZNCL2 AN ASYMMETRIC ENOLIZATION REACTIONS OF CHIRAL BASES
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DOI：
10.1016/0040-4039(95)00044-d
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发表时间：
1995-02-27
影响因子：
1.8
通讯作者：
SIMPKINS, NS
中科院分区：
文献类型：
--
作者：
COGGINS, P;GAUR, S;SIMPKINS, NS
在手性氨基锂碱3中加入ZnCl 2显著影响了在某些环酮的不对称烯醇化反应中观察到的不对称诱导水平，在加入Ca. 0.4但如果使用更多的ZnCl2，则该值再次降低。
The addition of ZnCl2 to the chiral lithium amide base 3 dramatically affects the level of asymmetric induction observed in asymmetric enolisation reactions of certain cyclic ketones, the enantiometic excess of aldol produce obtained increasing on addition of ca. 0.4 equivalents of ZnCl2 but men decreasing again if more ZnCl2 is employed.