Merkel cells are a touchy subject.

Merkel cells are a touchy subject.
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默克尔细胞是一个敏感的话题。

DOI:
10.1016/j.cell.2014.04.010
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发表时间:
2014
期刊:
影响因子:
64.5
通讯作者:
Ma,Qiufu
Ma,Qiufu
中科院分区:
生物学1区
文献类型:
--
作者:
Ma,Qiufu

文献摘要

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How the Merkel cell-neurite complex transduces and encodes touch remains unclear. Ikeda et al. now implicate Merkel cells as the primary sites of tactile transduction and the ion channel Piezo2 as the chief mechanotransducer. Surprisingly, Merkel cells also mediate allodynia, providing a new cellular target for chronic pain treatment.