EFFECT OF METRONIDAZOLE ON INTESTINAL MICROFLORA OF AMERICAN COCKROACH, PERIPLANETA-AMERICANA L
EFFECT OF METRONIDAZOLE ON INTESTINAL MICROFLORA OF AMERICAN COCKROACH, PERIPLANETA-AMERICANA L
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DOI：
10.1128/aac.13.1.115
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发表时间：
1978-01-01
影响因子：
4.9
通讯作者：
MARKOVETZ, AJ
中科院分区：
文献类型：
--
作者：
BRACKE, JW;CRUDEN, DL;MARKOVETZ, AJ
蟑螂[P.给予了美国甲硝唑的抗菌剂，该抗菌药物专门针对厌氧菌。通过光和扫描电子显微镜，细菌学检查和甲烷形成评估该药物的作用。从对照组中大大减少了生物和总数的类型。成年人的健康不受影响，但是在孵化的抗生素上维持的亚成人动物中发生了阻碍。脂肪体的细胞内细菌不受药物的影响。讨论了有关拟议的微生物宿主细胞外共生的结果。
Cockroaches [P. americana] were given the antimicrobial agent metronidazole which acts specifically against anaerobes. The effect of the drug was assessed by light and scanning electron microscopy, bacteriological examination and methane formation. Types of organisms and total numbers were greatly reduced from controls. The health of mature adults was unaffected, but stunting occurred in subadult animals maintained on the antibiotic from hatching. The intracellular bacteria of the fat body were not affected by the drug. The results are discussed with respect to a proposed microbe-host extracellular symbiosis.