Effect of electrical stimulation on chronic leg ulcer size and appearance
Effect of electrical stimulation on chronic leg ulcer size and appearance
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DOI：
10.1093/ptj/83.1.17
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发表时间：
2003-01-01
期刊：
影响因子：
3.2
通讯作者：
Harris, KA
中科院分区：
文献类型：
--
作者：
Houghton, PE;Kincaid, CB;Harris, KA
背景和目的。电流已被推荐用于慢性压力性溃疡;然而，电流的能力。这种改善其它类型慢性溃疡愈合的方式还没有很好地建立起来。本研究的目的是检查高压脉冲电流（HVPC）对慢性小腿溃疡愈合的影响。科目27名患有42个慢性腿部溃疡的人参加了这项研究。方法.受试者被分开。根据伤口的主要病因（糖尿病、动脉功能不全、静脉功能不全）分为亚组，然后。随机分配接受HVPC（100微秒，150 V，100 Hz）或假治疗45分钟，每周3次，持续4周。在初始检查期间，在1- 2周的时间内，受试者仅接受常规伤口治疗，在4周的假手术或HVPC治疗后，以及在治疗后1个月，评估伤口表面积和伤口外观。结果结果表明，HVPC应用于慢性腿部溃疡，在4周的治疗期内将伤口表面积减少到初始伤口大小的约一半（平均降低= 44.3%，SD= 8.8%，范围=2.8%-100%），这是在用假手术装置治疗的伤口中观察到的2倍以上（平均降低= 16.0%，SD= 8.9%，范围=-30.3%-83.7%）。讨论和结论。研究结果表明，应考虑每周给予3次HVPC，以加速慢性腿部溃疡的伤口闭合。
Background and Purpose. Electrical current has been recommended for use on chronic, pressure ulcers; however, the ability of. this modality to improve healing of other types of chronic ulcers is less well established. The purpose of this study was to examine the effect of high-voltage pulsed current (HVPC) on, healing of chronic leg ulcers. Subjects. Twenty-seven, people with 42 chronic leg ulcers participated in the study. Methods. The subjects were separated. into subgroups according to primary etiology of the wound (diabetes, arterial insufficiency, venous insufficiency) and then. randomly assigned to receive either HVPC (100 microseconds, 150 V, 100 Hz) or a sham treatment for 45 minutes, 3 times weekly, for 4 weeks. Wound surface area and wound appearance were assessed during an initial examination, following a 1- to 2-week period-during which subjects received only conventional wound therapy, after, 4, weeks of sham or HVPC treatment, and at 1 month following treatments. Results. The results indicated that HVPC applied to chronic leg ulcers reduced the wound surface area over the 4-week treatment period to approximately one half the initial wound size (mean decrease=44.3%, SD=8.8%, range=2.8%-100%), which was over 2 times greater than that observed in wounds treated with sham units (mean decrease=16.0%, SD=8.9%, range=-30.3%-83.7%). Discussion and Conclusion. The results of the study indicate that HVPC administered 3 times a week should be considered to accelerate wound closure of chronic leg ulcers.