Quadrant distribution of dysplastic nevus syndrome.
Quadrant distribution of dysplastic nevus syndrome.
复制标题
发育不良痣综合征的象限分布。
作者：
Wolfram Sterry;E. Christophers
一个59岁的男子与许多聚集色素病变局限于左上象限他的身体描述。病变包括雀斑样痣、常见获得性痣和发育不良痣。此外，在这个象限内，两个恶性黑色素瘤在不同阶段的进展发展，从发育不良痣。本例为迄今未见报道的象限型发育不良痣综合征。由于象限综合征是由于单突变，我们的观察强烈支持的概念，一个常染色体显性遗传性状的发育不良痣综合征。
A 59-year-old man with numerous aggregated pigmented lesions confined to the left upper quadrant of his body is described. The lesions consist of lentigines, common acquired nevi, and dysplastic nevi. In addition, within this quadrant two malignant melanomas at different stages of progression developed from dysplastic nevi. This patient presents a hitherto undescribed quadrant type of dysplastic nevus syndrome. As quadrant syndromes are due to single mutations, our observation strongly supports the concept of an autosomal-dominant trait in dysplastic nevus syndrome.