Response properties of single cells in monkey striate cortex during reversible inactivation of individual lateral geniculate laminae.
Response properties of single cells in monkey striate cortex during reversible inactivation of individual lateral geniculate laminae.
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DOI：
10.1152/jn.1981.46.5.1102
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发表时间：
1981-11
影响因子：
2.5
通讯作者：
J. Malpeli;P. Schiller;C. Colby
中科院分区：
文献类型：
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作者：
J. Malpeli;P. Schiller;C. Colby
在恒河猴和其他几种哺乳动物中，已经描述了三种不同类型的视网膜神经节细胞，即X细胞、Y细胞和W细胞。这些细胞的中枢投射是非常特殊的：X细胞投射到小细胞外侧膝状核(LGN)；Y细胞投射到大细胞LGN和上丘；W细胞主要投射到上丘(2，13，14，16)。X和Y通道的空间分离在它们向纹状皮质的投射中保持不变。小细胞(X细胞)轴突分布在4C-p层，而大细胞(Y细胞)轴突终止于4C-cu层(7)。除了纹状皮质的输入阶段之外，人们对这些通路的特异性知之甚少，尽管已经表明皮质顶盖通路是由大细胞输入主导的。有人认为，X、Y和W细胞通道在整个视觉皮质中仍然是不同的，皮质细胞的许多感受野特性来自于它们接收的Len输入的类别，而不是来自皮质内回路(有关最近的综述，请参阅参考文献)。21)在平行加工假说的第一个也是最强的形式中，Hoffman和Stone(5)提出简单细胞由X细胞驱动，复杂细胞由Y细胞驱动。另一种方法是假设这些平行输入在皮质中相互作用，产生特定的感受场属性，Marr(10)预测，沿着这些线，Y细胞通过抑制动作负责在皮质中建立方向性特异性。
In the rhesus macaque, as in several other mammalian species, three distinct classes of retinal ganglion cells have been described, X-, Y-, and W-cells. The central projections of these cells are quite specific: the X-cells project to parvocellular lateral geniculate nucleus (LGN); the Y-cells to magnocellular LGN and to superior colliculus; the W-cells primarily to the superior colliculus (2, 13, 14, 16). The spatial segregation of the X and Y channels is maintained in their projections to the striate cortex. Parvocellular (X-cell) axons arborize in layer 4C-p while magnocellular (Y-cell) axons terminate in 4C-cu (7). Beyond the input stage in striate cortex little is known about the specificity of these pathways, although it has been shown that the corticotectal pathway is dominated by magnocellular inputs (15). It has been suggested that X-, Y-, and W-cell channels remain distinct through visual cortex and that many of the receptive-field properties of cortical cells derive from the class of LEN input they receive rather than from intracortical circuitry (for a recent review see Ref. 21) In the first and strongest form of the parallel-processing hypothesis, Hoffman and Stone (5) proposed that simple cells are driven by X-cells and complex cells by Y-cells. An alternative approach is to assume that these parallel inputs interact in cortex to produce particular receptive-field properties, Along these lines, Marr (10) has predicted that Y-cells are responsible, by inhibitory actions, for setting up directional specificity in cortex.