New insights into intrinsic foot muscle morphology and composition using ultra-high-field (7-Tesla) magnetic resonance imaging.
New insights into intrinsic foot muscle morphology and composition using ultra-high-field (7-Tesla) magnetic resonance imaging.
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DOI：
10.1186/s12891-020-03926-7
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发表时间：
2021-01-21
影响因子：
2.3
通讯作者：
Collins NJ
中科院分区：
文献类型：
--
作者：
Franettovich Smith MM;Elliott JM;Al-Najjar A;Weber KA 2nd;Hoggarth MA;Vicenzino B;Hodges PW;Collins NJ
足部的内在肌肉是足部功能的关键因素，在下肢疾病中进行评估非常重要。磁共振成像（MRI）提供了一种非侵入性的选择来测量肌肉形态和组成，这是肌肉功能的主要决定因素。超高场（7-T）磁共振成像提供了足够的信号，以评估内在的足部肌肉的形态，并且，当与化学位移序列相结合时，可以获得肌肉成分的测量。在这里，我们的目标是提供一个概念验证的方法来测量内在的足部肌肉形态和组成与高场MRI。一名健康女性（年龄39岁，体重65 kg，身高1.73 m）接受了MRI。在Siemens 7 T STIMTOM扫描仪和3 T STIMTOM Prisma扫描仪上采集全足的T1加权VIBE -射频破坏3D稳态GRE -序列以进行比较。还使用7 T下的3D 2点狄克逊序列获取高分辨率脂肪/水分离图像。比较3 T和7 T扫描机的冠状面图像。使用3D Slicer软件，在7 T图像上手动勾画每块肌肉的感兴趣区域。计算每块肌肉的肌肉体积和肌肉脂肪浸润百分比（肌肉脂肪浸润% =脂肪/（脂肪+水）x100）。与3 T图像相比，7 T图像提供了更高的上级分辨率，特别是在前足，以促进单个肌肉的分割。肌肉体积范围为1.5 cm 3和19.8 cm 3，肌肉脂肪浸润百分比范围为9.2- 15.0%。这项概念验证研究证明了一种可行的方法，使用先进的高场MRI技术量化肌肉形态和组成的个人内在脚肌肉。这种方法可以用于未来的研究，以更好地了解内在的足部肌肉形态和组成的健康个体，以及那些较低的疾病。
The intrinsic muscles of the foot are key contributors to foot function and are important to evaluate in lower limb disorders. Magnetic resonance imaging (MRI), provides a non-invasive option to measure muscle morphology and composition, which are primary determinants of muscle function. Ultra-high-field (7-T) magnetic resonance imaging provides sufficient signal to evaluate the morphology of the intrinsic foot muscles, and, when combined with chemical-shift sequences, measures of muscle composition can be obtained. Here we aim to provide a proof-of-concept method for measuring intrinsic foot muscle morphology and composition with high-field MRI. One healthy female (age 39 years, mass 65 kg, height 1.73 m) underwent MRI. A T1-weighted VIBE – radio-frequency spoiled 3D steady state GRE – sequence of the whole foot was acquired on a Siemens 7T MAGNETOM scanner, as well as a 3T MAGNETOM Prisma scanner for comparison. A high-resolution fat/water separation image was also acquired using a 3D 2-point DIXON sequence at 7T. Coronal plane images from 3T and 7T scanners were compared. Using 3D Slicer software, regions of interest were manually contoured for each muscle on 7T images. Muscle volumes and percentage of muscle fat infiltration were calculated (muscle fat infiltration % = Fat/(Fat + Water) x100) for each muscle. Compared to the 3T images, the 7T images provided superior resolution, particularly at the forefoot, to facilitate segmentation of individual muscles. Muscle volumes ranged from 1.5 cm3 and 19.8 cm3, and percentage muscle fat infiltration ranged from 9.2–15.0%. This proof-of-concept study demonstrates a feasible method of quantifying muscle morphology and composition for individual intrinsic foot muscles using advanced high-field MRI techniques. This method can be used in future studies to better understand intrinsic foot muscle morphology and composition in healthy individuals, as well as those with lower disorders.
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DOI：
10.1016/j.foot.2013.07.001
发表时间：
2013-12-01
期刊：
Foot (Edinburgh, Scotland)
影响因子：
--
作者：
Green, S M;Briggs, P J
通讯作者：
Briggs, P J
影响因子：
2.6
作者：
Feger, Mark A.;Snell, Shannon;Hertel, Jay
通讯作者：
Hertel, Jay
影响因子：
3
作者：
Elliott, James;Jull, Gwendolen;Gibbon, Wayne W.
通讯作者：
Gibbon, Wayne W.
影响因子：
16.2
作者：
Bus, Sicco A.;Maas, Mario;Levi, Marcel
通讯作者：
Levi, Marcel
影响因子：
1.7
作者：
Feger, Mark A.;Donovan, Luke;Hertel, Jay
通讯作者：
Hertel, Jay